News versetzen ABIO in ein neues Zeitalter

March 26, 2010 - 8:30 AM EDT

      ABIO§5.60    2.95


ARCA biopharma Announces Patent Issued for Treating Heart Failure Patients with Bucindolol Based on Genetic Testing
Revised Request for FDA Special Protocol Assessment for GencaroTM Development in Genotype-defined Heart Failure Population Submitted
Mar. 26, 2010 (Business Wire) -- ARCA biopharma, Inc. (Nasdaq: ABIO), a biopharmaceutical company developing genetically targeted therapies for heart failure and other cardiovascular diseases, today announced that the U.S. Patent and Trademark Office (USPTO) has issued a patent on methods of treating heart failure patients with bucindolol based on genetic testing. The patent (USP# 7,678,824) entitled “Methods for Treatment with Bucindolol Based on Genetic Targeting,” provides protection in the United States for this novel approach to treating patients with heart failure, one of the largest health care problems in the United States and the rest of the world. ARCA had previously announced the notice of allowance of this patent. Industry sources estimate that approximately 5.7 million Americans have heart failure and nearly 670,000 new patients are diagnosed annually. In addition, heart failure is the underlying reason for approximately 12 to 15 million annual visits to physicians, 6.5 million annual hospital days and over $37 billion in direct and indirect healthcare costs in the United States.

“We are obviously pleased with the USPTO’s issuance of this patent which we believe will extend our pharmacogenetic intellectual property protection around bucindolol and, if approved for marketing, provide Gencaro market exclusivity into 2025,” said Michael R. Bristow, President and Chief Executive Officer of ARCA. “Chronic heart failure continues to be a major health care problem, and among the challenges to improving care is the uncertainty of patient responses to drug treatment. We believe that a new heart failure therapy that includes a simple test to identify a substantial subpopulation of patients more likely to benefit has the potential to help alleviate some of the problems encountered with the current standard of practice.”

On March 25, 2010, ARCA submitted a revised clinical study protocol for review under the U.S. Food and Drug Administration’s (FDA) Special Protocol Assessment (SPA) process for the design of a clinical trial to assess the safety and efficacy of Gencaro in approximately 3,200 patients with chronic heart failure who have the genotype that appears to respond most favorably to Gencaro. An SPA is an agreement with the FDA that the proposed trial protocol design, clinical endpoints and statistical analyses are acceptable to support regulatory approval. Any proposed trial protocol must be reviewed and agreed upon with the FDA and the final trial protocol may be significantly different from the Company’s SPA submission. If ARCA obtains sufficient funding and FDA approval of the SPA, ARCA currently expects it could begin the proposed clinical trial approximately one year after such funding and approval. The FDA has previously designated as a Fast Track development program the investigation of Gencaro for the reduction of cardiovascular mortality and cardiovascular hospitalizations in a genotype-defined heart failure population.  

ABIO hat nur 7,62 Millionen O/S

Bis jetzt(heute) gehandelt 6,2 Millionen Shares.  

http://www.advfn.com/...&s=NASDAQ:abio&p=0&t=37&vol=1  

Also ich muß da mal selber tiefer recherchieren denn in den USA im Yahoo-Board werden unglaubliche Kursziele genannt nämlich 50 - 120 Dollar und das nur wenn es ein Aproval für die USA gibt.Was soll passieren wenn es ein weltweites Aproval gibt?

rt 6,25 Dollar.  

mal beobachten  

 

Jetzt ist schon der gesamte Freefloat gehandelt worden und es sind erst knapp 2 Stunden gehandelt worden.

Selten so etwas gesehen.  

GIGANTISCH  

gegen chronische Herzinsuffizienz hergestellt/entwickelt. Darunter leiden wohl 5,7 Millionen Amerikaner und noch vielmehr weltweit...  

one of the largest health care problems in the United States

eines der größten Gesundheitsprobleme der USA und dem Rest der Welt. Und die haben ein Mittel dagegen  

ist aber kein Hot Stock ;))

ist ein Nasdaq Wert und kein OTC BB Titel, gehört also ins seriöse Board  

Gehandelt jetzt schon gigantische : 11,5 Millionen Aktien bei 7,5 Millionen O/S  

was geht denn bitte hier ab?

RT 9 USD  

Ist mir bei der Threaderöffnung dadurchgegangen.

Mal schauen obs die MODs ins Börsenforum schieben.  

es handelt sich hierbei übrigens nur um ein PATENT!  

hat jemand von euch shares?  

Ende 2006 lag die Aktie mal bei um die 400 Dollar zumindest laut Chart von Comdirekt. Dort ist auch zu der Zeit kein Split eingezeichnet also wirds wohl stimmen.  

 

Hat jemand ein RT Link?

Ich bin auch drinnen!

Ja bin heute zu 4,43 Dollar rein. Glück gehabt würd ich sagen  

ein Patent über "Methods for Treatment with Bucindolol Based on Genetic Targeting"

wie dem auch sei, es hilft gegen die Krankheit  

bist Du dabei, hast Du Aktien gekauft?  

kurs zieht wieder an  

ich schaff das jedes mal :-)