Einstieg lohnenswert
Hoffentlich nur meine Meinung!
Aber ein guter Versuch!
Aber diese Masche reiten noch Andere;
Maier & Partner, Heidelberg Pharma usw!
Aber die Anleger lassen sich natürlich nicht verarschen; wie immer!
https://seekingalpha.com/news/...ceuticals-files-for-150m-mixed-shelf
Tonix Pharmaceuticals files for $150M mixed shelf
Apr. 8, 2020 6:35 PM ET|About: Tonix Pharmaceuticals ... (TNXP)
Tonix Pharmaceuticals (NASDAQ:TNXP) has filed a prospectus for a $150M mixed shelf offering.
Warum sonst stehen hier 150 Million Dollar im Raum ?
Ist ein Investor drauf und dran einzusteigen ?
Wer weiß was dazu ?
Mal sehen - und ob - hier ein großer Fisch einsteigt - und mal eben die Firma Quasi übernimmt,
und fast den 4 -fachen Preis der aktuellen MCAP bezahlt.
Wenn klar ist wer , wo , hier einsteigt - denke ich - wird der Kurs nicht mehr zu halten sein,
zudem dann wohl auch klar sein dürfte das ein Impfstoff gegen COVID-19 gefunden scheint ?!?
Eure Meinungen dazu.?
Bleibt gesund und trotz der angespannten Lage Frohe Ostern.
Seit heute sind Infos zum Impfstoff TNX-1800 Covid-19 Vaccine wieder online.
Zudem kommt ein 150 Million Dollar Offering. Für was das Geld wohl gebraucht wird ??
Am 01.05. ist das jährliche Shareholder-Meeting.
Bin gespannt auf die nächsten Tage.
X Auszug von der Homepage X
TNX-1800 (Coronavirus Vaccine)
Scientific Rationale for TNX-1800 as a vaccine for coronavirus
TNX-1800 (live modified horsepox virus vaccine) is being developed by Tonix Pharmaceuticals in a strategic collaboration with Southern Research to support the development of a vaccine to protect against the new coronavirus disease, COVID-19. TNX-1800 is based on Tonix’s proprietary horsepox vaccine platform. It is believed that horsepox has the potential to serve as a vector for vaccines to protect against other infectious agents. The new research collaboration will develop and test a potential horsepox vaccine that expresses protein from the virus that causes COVID-19 to protect against the disease.
About TNX-801* and TNX-1800*
TNX-801 is a live virus vaccine based on synthesized horsepox1,2. TNX-1800 is a modified horsepox virus that is designed to express a protein from the virus that causes COVID-19, which is known as SARS-CoV-2. Molecular analysis suggests that TNX-801 has relatively “complete” left and right inverted terminal repeats (ITRs) while different vaccinia isolates have a variety of deletions in the left and right ITRs. Therefore, TNX-801 has additional genes, relative to vaccinia vaccines, that may play roles in host immune interactions and one or more of such proteins may serve as antigens for protective immunity. Molecular analysis also shows that horsepox is closer than modern vaccines in DNA sequence to the vaccine discovered and disseminated by Dr. Edward Jenner2,3,4. No new gene elements were added to the natural isolate and the small plaque size in culture appears identical to the U.S. Centers for Disease Control publication of the natural isolate5. Relative to vaccinia, horsepox has substantially decreased virulence in mice1. TNX-801 vaccinated macaques showed no overt clinical signs after monkeypox challenge6.
*TNX-801 and TNX-1800 are in the pre-IND stage and have not been approved for any indication.
About Orthopoxvirus Vectors
Horsepox and vaccinia are closely related orthopoxvirus that are believed to share a common ancestor. The name “horsepox” was derived from the animal from which the virus was isolated. The natural host is presumed to be wild rodents. The name “vaccinia” is a term that is applied to a group of related vaccine viruses that were industrially produced by infecting cows. The terms “vaccinia” and “vaccine” were originally coined by Dr. Edward Jenner (derived from the Latin “vacca” for “a cow”) in his description of an illness in cows (cowpox) that was transferred inadvertently by human hands from horses to cows and from cows to human hands. Jenner was the first to use infectious matter (vaccinia or vaccine) from cowpox to elicit protective immunity to smallpox by intentional “vaccination”. Although horsepox is not considered to be a vaccinia, modern DNA analysis reveals more variation between different vaccinia strains than between horsepox and certain vaccinia strains. Live replicating orthopoxvirus, like vaccinia or horsepox, can be engineered to express foreign genes and have been explored as platforms for vaccine development because they possess; (1) large packaging capacity for exogenous DNA inserts, (2) precise virus-specific control of exogenous gene insert expression, (3) lack of persistence or genomic integration in the host, (4) strong immunogenicity as a vaccine, (5) ability to rapidly generate vector/insert constructs, (6) readily manufacturable at scale, and (7) ability to provide direct antigen presentation.
Click here to learn more about Coronavirus
What makes TNX-1800 unique?
TNX-1800, as a horsepox vaccine, has potential advantages over vaccinia-based vaccines, including:
Maintains strong immunogenicity with potentially improved tolerability
Relative to non-replicating vaccinia, horsepox’s replication in human cells provides direct antigen presentation by Class I MHC
Horsepox may behave differently as a vector, in part because of its different repertoire of genes that modulate immune responses and host range
Development Status
TNX-1800 is being developed by Tonix Pharmaceuticals in a strategic collaboration with Southern Research, an independent, 501(c)(3) nonprofit, scientific research organization.
Basis for Exclusivity
Tonix recently filed a provisional patent on TNX-1800’s technology. In addition, we expect TNX-1800 to be eligible for 12 years of non-patent-based exclusivity under the Patient Protection and Affordable Care Act, or PPACA.
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Wertpapier: Tonix Pharmaceuticals C |
Ich glaub eher dran - das TNXP bereits einen Großteil des Offerings von 150 m Dollar - bereits angeboten bekommen hat. Einfach aus dem Nix 150 Mill. Dollar einsammeln, ist nicht so einfach - ich meine,
da ist im Hintergrund bereits was vorbereitet worden, von einigen Seiten.
Zudem glaub ich ( und hoffe ) das bald 1-2 Hammer-News dieses Offering unterstützen werden.
Sobald der Kurs über 1 Dollar bzw. 2 Dollar geht - ist er nicht mehr zu halten, und kann durchaus
auf 4-6 Dollar irgendwo ansteigen ! Viel Wunsch und Hoffnung von mir auch dabei. Klar.
Aber wir haben dies schon oft in der letzten Zeit gesehen wenn es um CV-Stocks ging.
Good Luck.
Wäre mal an der Zeit, das wir Richtung 1,50-2,00 Euro hochlaufen.
Kann je nach News, ganz plötzlich passieren - und eigentlich sind News bei Tonix überfällig.....
Viel Glück.