Calypte Only Company with Full Menu of Tests.

LAKE OSWEGO, Ore., July 13 /PRNewswire-FirstCall/ -- Calypte Biomedical Corporation (Amex: HIV) (the "Company"), medical diagnostic tests manufacturer for the professional point of care (PRO) and over the counter (OTC) segments of the market for the detection of antibodies to the human immunodeficiency virus (HIV), announced today that it has received an initial order for 35,500 units of its Aware(TM) HIV-1/2 oral fluid rapid test. This initial order has been placed through Gennaria Comercio International Lda on behalf of MineSeeker Foundation and will be sold through Calypte's exclusive distributors in Africa once final destinations are known. Calypte currently has approval to sell its rapid oral fluid test in South Africa and Kenya. Based on Calypte's communications with MineSeeker, this is the first firm order of a series of orders totaling 1.0 million tests that MineSeeker intends placing with Calypte over the next 12 months.

Gennaria represents several humanitarian organizations, including MineSeeker, which plans to launch a large-scale HIV testing initiative in Africa beginning this September.

Nelson Mandela said: "As a patron of MineSeeker, I totally support the AIDS test initiative. The tests will remove the fear of many people who believe they may be infected and who are nervous about blood testing. Fear is a terrible affliction, whether it is the fear of treading on a mine or the fear not knowing if you are HIV positive."

Roger I. Gale, Calypte's Chairman and Chief Executive Officer commented, "We have long believed we have been developing an effective solution in the battle against HIV/AIDS with a non-invasive rapid diagnostic test. Now that we are receiving approvals in HIV-stricken areas in Sub-Saharan Africa, we are targeting humanitarian organizations that want to make significant contributions in the fight against AIDS."

Mr. Mike Kendrick, founder of MineSeeker, stated, "The intended first order of 1 million tests is part of a larger MineSeeker initiative to deliver 5 million HIV oral fluid rapid tests to Africa. The purchase of the initial 1 million Aware(TM) HIV-1/2 oral swab rapid tests will be donated to NGOs for distribution in the field or sold, at cost."

Mr. Kendrick continued, "While the primary objective of MineSeeker is the eradication of land mines, we are also committed to the regeneration of the local communities. Without that, the clearance of mines is only part of the answer. Land will be returned to the people to grow food and a foster management program installed to help re-establish themselves. This will mean growing good quality crops that will lift the natural immunity system -- particularly helping AIDS sufferers. The introduction of the Aware(TM) product will help re-build the confidence of these communities."

About MineSeeker Foundation:

The MineSeeker Foundation (www.mineseeker.com) is primarily involved with the removal of land mines. The foundation has a new initiative, the 'Sole of Africa' initiative, which includes returning mine free land back to agriculture and an educational and empowerment program that trains local people to farm and vocational training for people unable to find work, including land mine and AIDS victims.

The MineSeeker Foundation Patrons include Nelson Mandela, Sir Richard Branson, Queen Noor of Jordon, Graca Machel, John Paul Dejoria and Brad Pitt. The Foundation is supported by other leading NGOs including 'Feed the Children', The International Youth Foundation and The Salvation Army.

About Calypte Biomedical:

Calypte Biomedical Corporation (www.calypte.com) is a U.S.-based healthcare company focused on the development and commercialization of diagnostic testing products for the detection of sexually transmitted diseases such as the HIV-1 BED Incidence EIA and new diagnostic test products for the rapid detection of HIV and other sexually transmitted diseases, several of which do not require blood samples. Calypte believes there is a significant need for rapid detection of such diseases globally to control their proliferation, particularly in developing countries, which lack the medical infrastructure to support laboratory-based testing. Calypte believes that testing for HIV and other sexually transmitted infectious diseases may make important contributions to public health, and could increase the likelihood of treating those with undetected HIV and other sexually transmitted diseases.

Statements in this press release that are not historical facts are forward-looking statements within the meaning of the Securities Act of 1933, as amended. Those statements include statements regarding the intent, belief or current expectations of the Company and its management. Such statements reflect management's current views, are based on certain assumptions and involve risks and uncertainties. Actual results, events, or performance may differ materially from the above forward-looking statements due to a number of important factors, and will be dependent upon a variety of factors, including, but not limited to, the Company's ability to obtain additional financing, if and as needed, and access funds from its existing financing arrangements that will allow it to continue its current and future operations and whether demand for its test products in domestic and international markets will generate sufficient revenues to achieve positive cash flow and profitability. The Company undertakes no obligation to publicly update these forward-looking statements to reflect events or circumstances that occur after the date hereof or to reflect any change in the Company's expectations with regard to these forward-looking statements or the occurrence of unanticipated events. Factors that may impact the Company's success are more fully disclosed in the Company's most recent public filings with the U.S. Securities and Exchange Commission ("SEC"), including its annual report on Form 10-KSB for the year ended December 31, 2005 and its subsequent filings with the SEC.